About the project:

An open data platform to explore a drug repurposing collection of over 12,000 drugs and related knowledge from Clarivate Integrity, GVK Excelra GoStar, and Adis Pharmacovigilance


View the project

reframedb.org


Publication

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Jeff Janes, Megan E Young, Emily Chen, Nicole H Rogers, Sebastian Burgstaller-Muehlbacher, Laura D Hughes, Melissa S Love, Mitchell V Hull, Kelli L Kuhen, Ashley K Woods, Sean B Joseph, H Michael Petrassi, Case W McNamara, Matthew S Tremblay, Andrew I Su, Peter G Schultz, Arnab K Chatterjee. Proceedings of the National Academy of Sciences of the United States of America, 115, 42, 10750-10755.
PubMed ID: 30282735 DOI: 10.1073/pnas.1810137115


Code

github.com/sebotic/repurpos.us